Advertisement

Increasing the efficacy of antiepileptic effect of diazepam by cerebellar cortex electrostimulation

  • A. I. Brusentsov
Pharmacology and Toxicology
  • 19 Downloads

Abstract

Diazepam effects on epileptic foci induced by benzylpenicillin application to the posterior sigmoid gyrus were studied in acute experiments on cats. Diazepam more effectively decreased the activity of the foci after preliminary electrostimulation of the IX and X lobules of the vermis than without such a pretreatment.

Key Words

diazepam cerebellum electrostimulation epileptic activity 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    G. N. Kryzhanovskii, A. A. Shandra, and L. S. Godlevskii,Uspekhi Fiziol. Nauk,21, No. 3, 38–58 (1990).Google Scholar
  2. 2.
    G. N. Kryzhanovskii A. A. Shandra, L. S. Godlevskii, and A. M. Mazarati, —Ibid.,,23, No. 3, 38–59 (1992).Google Scholar
  3. 3.
    I. B. Gartside,Electroencephalogr. Clin. Neurophysiol.,44, No. 3, 373–379 (1978).PubMedCrossRefGoogle Scholar
  4. 4.
    G. N. Kryzhanovsky,Central Nervous System Pathology: A New Approach, New York (1986).Google Scholar
  5. 5.
    O. Larsell,J. Comp. Neurol.,99, No. 1, 135–199 (1953).PubMedCrossRefGoogle Scholar
  6. 6.
    W. Losher, C. Rundfeld, and D. Honack,Epilepsy Res.,15, 207–219 (1993).CrossRefGoogle Scholar
  7. 7.
    A. A. Shandra, A. M. Mazarati, L. S. Godlevsky, and R. S. Vastyanov,Epilepsia,37, No. 3, 269–274 (1996).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • A. I. Brusentsov
    • 1
  1. 1.Odessa State Medical UniversityOdessaUSSR

Personalised recommendations