Abstract
Titers of autoantibodies to nerve growth factor, water-soluble astrocytic protein S-100, glial fibrillary acidic protein, and MP-65 membrane protein of the nervous cell superfamily of integrins was determined by solid-phase immunoenzyme assay in healthy children and in children with the Romano-Ward and sick sinus syndromes. Immunoreactivity to these antigens was either increased or decreased in 20% of sick children in comparison with that of healthy children of the same age.
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A. B. Poletaev, N. K. Vabishchevich, S. M. Pyatigorskaya,Method of Screening Examination of Women at Infant Delivering Age with the Help of Test System ELI-P to Prognosticate Healthy or Abnormal Embryonic and Fetal Development [in Russian]. Russia Federation Inventor's Certificate no. 95105847/14(010520)(RF),Pospatent, Moscow (1997).
V. M. Bashina, N. L. Gorbachevskaya, T. P. Klyshnik,et al., Istselenie,2, 440–443 (1995).
N. A. Belokon' and M. B. Kuberger,Cardiovascular Diseases in Children [in Russian], Moscow (1987).
N. A. Belokon', S. B. Shvarkov, G. G. Osokina,et al., Pediatriya, No. 1, 37–41 (1986).
L. M. Makarov, Yu. M. Beloserov, M. A. Shkol'nikova,et al., Cardiologiya, No. 2, 31–33 (1993).
N. A. Plokhinskii,Biometric Algorithms [in Russian], Moscow (1980).
A. B. Poletaev, in: M. B. Shtark and M. V. Starostina, (Eds.),Monoclonal Antibodies in Neurobiology, [in Russian], Novosibirsk (1995), pp. 36–46.
V. A. Shul'man,et al., (Eds.),Sinus Node Weakness Syndrome, [in Russian], Krasnoyarsk (1995).
M. A. Shkol'nikova,Ros. Vestn. Perinatol. Pediatr., No. 2, 4–8 (1995).
S. Avrameas,Immunol. Today,12, 154–158 (1991).
J. S. Huston and A. Bugnami,Biochim. Biophys. Acta,493, 93–103 (1977).
R. Levi-Montalchini,EMBO J.,6, 1145–1154 (1987).
S. Rabizadeh, J. Oh, J. Yang,et al., Science,261, 345–348 (1993).
W. D. Snider,Cell,77, 627–638 (1994).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 677–679, June, 1998
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Klyushnik, T.P., Danilovskaya, E.V., Vatolkina, O.E. et al. Change in the titers of serum IgG-class autoantibodies to some nervous tissue proteins in patients with life-threatening arrhythmias. Bull Exp Biol Med 125, 601–603 (1998). https://doi.org/10.1007/BF02445252
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DOI: https://doi.org/10.1007/BF02445252