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Mechanisms of kindling induced by norbornan intoxication

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Single injection of norbornan induced kindling by disordering postsynaptic GABAergic structures. Modulation of GABAA receptor chlorine ionic channels is most crucial, while disturbances in postsynaptic low-affinity GABAA receptors are less important for this phenomenon. It is unlikely that GABAB, dopamine, and muscarinic neurotransmitter structures are involved into this process.

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Authors and Affiliations

  1. Department of Military Toxicology and Medical Protections, Laboratory of Perfluorocarbons, Military Medical Academy, St. Petersburg

    A. I. Golovko, M. B. Ivanov, O. A. Sviderskii, G. A. Sofronov & V. V. Shilov

Authors
  1. A. I. Golovko
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  2. M. B. Ivanov
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  3. O. A. Sviderskii
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  4. G. A. Sofronov
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  5. V. V. Shilov
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 653–656, June, 1998

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Golovko, A.I., Ivanov, M.B., Sviderskii, O.A. et al. Mechanisms of kindling induced by norbornan intoxication. Bull Exp Biol Med 125, 579–581 (1998). https://doi.org/10.1007/BF02445245

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  • DOI: https://doi.org/10.1007/BF02445245

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