Abstract
The study comparesin vitro effect of different contrast media on complement activity and eicosanoid content. Ionic agents (Bilignost>Iodamide>Triombrast>Hexabrix) exert pronounced complement-activating effect, while nonionic agents markedly increase blood content of arachidonic acid metabolites. The complement-activating effect of contrast media did not correlate with their ability to elevate blood content of prostaglandin F2α and leukotrienes C4 and B4.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 637–640, June, 1998
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Sergeev, P.V., Napolov, Y.K., Markina, E.V. et al. Comparativein vitro study of the effect of contrast media on complement activity and eicosanoid content in rat blood. Bull Exp Biol Med 125, 564–566 (1998). https://doi.org/10.1007/BF02445241
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DOI: https://doi.org/10.1007/BF02445241