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The energy supply systems in the heart valve leaflet cells during kryopreservation and storage

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The condition of animal heart valve allografts after kryopreservation and storage is assessed. After 2-day storage of preparations at 4°C tissue ATP content decreases by 1.5–2 times and remains at this level for 5 days. Freezing of tissues without kryoprotector results in more than 10-fold drop in ATP content and a 2-fold decrease in the total content of pyridine nucleotides. After kryopreservation these parameters decrease by 1.2–1.4 times.

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Authors and Affiliations

  1. Institute of Theoretical and Experimental Biophtsics, Russian Academy of Sciences, Pushchino

    V. S. Akatov, P. R. Makarov, V. V. Solov'ev & V. V. Teplova

  2. A. N Bakulev Research Center for Cardiovascular Surgery, Russian Academy of Medical Sciences, Moscow

    V. N. Terekhin, V. V. Zaitsev, R. M. Muratov & I. I. Skopin

Authors
  1. V. S. Akatov
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  2. P. R. Makarov
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  3. V. V. Solov'ev
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  4. V. V. Teplova
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  5. V. N. Terekhin
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  6. V. V. Zaitsev
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  7. R. M. Muratov
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  8. I. I. Skopin
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 631–633, June, 1998

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Akatov, V.S., Makarov, P.R., Solov'ev, V.V. et al. The energy supply systems in the heart valve leaflet cells during kryopreservation and storage. Bull Exp Biol Med 125, 558–560 (1998). https://doi.org/10.1007/BF02445239

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  • DOI: https://doi.org/10.1007/BF02445239

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