Abstract
Experiments on rats show that repeated bilateral microinjections of haloperidiol (5 μg) into globus pallidus or caudal neostriaum impair conditioned passive avoidance reaction and do not affect spontaneous motor activity. Unlike haloperidol injections to the rostral neostriatum, chronic blockade of the pallidal dopamineric system induces vegetative and trophic disturbances.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 615–617, June, 1998
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Yakimovskii, A.F. Repeated haloperidol microinjections to the globus pallidus induce vegetative components of parkinsonian syndrome in rats. Bull Exp Biol Med 125, 542–544 (1998). https://doi.org/10.1007/BF02445233
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DOI: https://doi.org/10.1007/BF02445233