Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 6, pp 1190–1193 | Cite as

Lipid peroxidation after acute intoxication of cats with anthio and the effect of ionol on their survival

  • I. A. Tarakanov
  • Ya. K. Kurambaev
  • M. M. Bordyukov
  • V. A. Safonov
General Pathology and Pathological Physiology
  • 15 Downloads

Abstract

Acute intoxication with the organophosphorus pesticide Anthio considerably increases the intensity of lipid peroxidation in Nembutal-anesthetized cats. Pretreatment with the synthetic antioxidant ionol prolongs the survival of the cats. Ionol has no appreciable effect on respiratory and hemodynamic parameters. Lipid peroxidation may contribute to the disturbances caused by Anthio.

Key Words

organophosphorus pesticide acute poisoning lipid peroxidation ionol cats 

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • I. A. Tarakanov
    • 1
  • Ya. K. Kurambaev
    • 1
  • M. M. Bordyukov
    • 1
  • V. A. Safonov
    • 1
  1. 1.Department of Respiratory Pathophysiology, Department of General Pathology of Nervous System, Institute of General Pathology and PathophysiologyRussian Academy of Medical SciencesMoscow

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