Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 2, pp 858–859 | Cite as

Inhibition of lipid peroxidation in synaptosomes from rat brain by peptide and protein fraction isolated from fetal human brain

  • A. M. Dupin
  • T. P. Klyushnik
  • E. V. Danilovskaya
  • A. N. Erin
  • E. M. Molnar
  • G. T. Sukhikh
Experimental Methods for Clinical Practice
  • 19 Downloads

Abstract

Peptide and protein fractions isolated from fetal human brain inhibit with different efficiency nonenzymatic lipid peroxidation in synaptosomes from rat brain. These fractions reciprocally capture the superoxide anion radicals generated in the reaction of 6-hydroxydopamine autooxidation.

Key Words

rat brain synaptosomes lipid peroxidation peptides and proteins of fetal brain 

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • A. M. Dupin
    • 1
  • T. P. Klyushnik
    • 1
  • E. V. Danilovskaya
    • 1
  • A. N. Erin
    • 1
  • E. M. Molnar
    • 1
  • G. T. Sukhikh
    • 1
  1. 1.International Institute of Biological Medicine, Research Center of Psychic HealthRussian Academy of Medical SciencesMoscow

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