Abstract
Stimulating effect of antiserotonin antibodies on phagocyte activity of peritoneal macrophages from C57B1/6 mice is demonstrated both after systemic administration and in a cell culture.In vitro experiments show that serotonin and antiserotonin antibodies exert similar effects. A possible mechanism of neurotropic effect of antiserotonin antibodies involving immunocompetent cells is discussed.
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References
V. V. Abramov,Immunologiya, No. 6, 11–15 (1995).
L. A. Basharova, L. A. Vetrile, V. A. Evseev,et al., Fiziol. Zh. SSSR,74, No. 10, 1367–1372 (1988).
L. A. Basharova, V. A. Evseev, L. A. Vetrile,et al., Byull. Eksp. Biol. Med.,115, No. 5, 469–471 (1993).
L. V. Devoino and R. Yu. Il'yuchenok,Monoaminergic Systems in the Regulation of Immune Reaction [in Russian], Novosibirsk (1982).
V. A. Evseev, L. A. Basharova, L. A. Vetrile,et al., Vopr. Narkol., No. 1, 33–39 (1995).
L. V. Koval'chuk and L. V. Gankovskaya,Immunologiya, No. 1, 4–7 (1995).
E. A. Korneva,Immunophysiology [in Russian], St. Petersburg (1993).
G. N. Kruzhanovskii and V. A. Evseev,Vestn. Acad. Med. Nauk SSSR, No. 3, 10–14 (1988).
G. N. Kruzhanovskii, V. A. Evseev, S. V. Magaeva,et al., Byull. Eksp. Biol. Med.,112, No. 11, 470–472 (1991).
V. G. Fomina and V. A. Lvseev,Zh. Mikrobiol., No. 10, 100–103 (1979).
H. Frimel,Immunological Methods [Russian translation], Moscow (1979).
R. Klein, M. Bansch, and P. A. Berg,Psychoneuroendocrinology,17, No. 6, 593–598 (1992).
K. S. Madden and D. L. Felten.Physiol. Rev.,75, No. 11, 77–106 (1995).
B. Pescar and S. Spector,Science,179, 1340–1341 (1973).
K. Schott, A. Batra, and R. Klem.Eur. Psychiatry,7, 209–211 (1992).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 12, pp. 663–665, December, 1997
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Mikovskaya, O.I., Fomina, V.G., Basharova, L.A. et al. Antiserotonin antibodies as stimulators of mouse peritoneal macrophages. Bull Exp Biol Med 124, 1211–1213 (1997). https://doi.org/10.1007/BF02445122
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DOI: https://doi.org/10.1007/BF02445122