Abstract
Effect of pancreatic lipase on supramolecular DNA complexes, nuclear matrix, and 70% ethanol-fixed cells is studied by elastoviscosimetry. It is shown that lipase induces DNA degradation not onlyin vitro but also in whole cells. Possible role of neutral lipids, in particular, DNA-bound diglycerides, in the arrangement of chromosomal DNA is discussed.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 12, pp. 635–639, December, 1997
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Struchkov, V.A., Strazhevskaya, N.B. Effect of pancreatic lipase on supramolecular DNA complexes in eukaryotic cellsin vivo andin situ . Bull Exp Biol Med 124, 1185–1188 (1997). https://doi.org/10.1007/BF02445115
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DOI: https://doi.org/10.1007/BF02445115