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Correction of duodenal smooth muscle contractility with methacin and proserin in ulcer

  • Experimental Biology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The aftereffects of experimental damage to the duodenal wall on the contractility are studied in isolated rat duodenum. Development of ulcer was associated with replacement of rhythmic contractions by slow-wave tonic activity. Methacin and proserin accelerate the repair processes and potentiate the compensatory reactions, promoting the shift of spontaneous activity of smooth muscles toward the slow part of the spectrum.

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Authors and Affiliations

  1. I. M. Sechenov Institute of Evolutional Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg

    S. V. Kuznetsov & N. N. Kuznetsova

  2. Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg

    S. V. Kuznetsov & N. N. Kuznetsova

Authors
  1. S. V. Kuznetsov
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  2. N. N. Kuznetsova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 215–220, August, 1997

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Kuznetsov, S.V., Kuznetsova, N.N. Correction of duodenal smooth muscle contractility with methacin and proserin in ulcer. Bull Exp Biol Med 124, 811–815 (1997). https://doi.org/10.1007/BF02445101

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  • DOI: https://doi.org/10.1007/BF02445101

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