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Parameters of hemostasis and blood lysosomal enzyme activity in allergic necrotizing inflammation against the background of suppression and stimulation of immune processes

  • General Pathology and Pathological Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Changes in the hemostasis system are experimentally shown in rabbits with modeled allergic inflammation (Arthus phenomenon) of the maxilla. Suppression of immune processes has an adverse effect on this system, while immunostimulation improves hemostatic parameters. Immunosuppression impairs lysosomal mechanisms of inflammation, while stimulation of the immune system normalizes these mechanisms.

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Authors and Affiliations

  1. Department of Pathological Physiology, Russian University of Peoples' Friendship, Moscow

    A. M. Avanesov, G. A. Drozdova, G. M. Drogova, A. V. Pasechnik & V. A. Frolov

  2. Department of Maxillofacial Surgery and Stomatology, Russian University of Peoples' Friendship, Moscow

    A. M. Avanesov, G. A. Drozdova, G. M. Drogova, A. V. Pasechnik & V. A. Frolov

Authors
  1. A. M. Avanesov
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  2. G. A. Drozdova
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  3. G. M. Drogova
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  4. A. V. Pasechnik
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  5. V. A. Frolov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 157–160, August, 1997

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Avanesov, A.M., Drozdova, G.A., Drogova, G.M. et al. Parameters of hemostasis and blood lysosomal enzyme activity in allergic necrotizing inflammation against the background of suppression and stimulation of immune processes. Bull Exp Biol Med 124, 760–763 (1997). https://doi.org/10.1007/BF02445084

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  • DOI: https://doi.org/10.1007/BF02445084

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