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Effect of interleukin-1β on platelet aggregation in August, Wistar, and WAG rats in acute emotional stress

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Acute emotional stress inhibits platelet aggregation in August and WAG rats and reduces it in Wistar rats. Functional parameters of platelets are altered predominantly in passive rats. Interleukin-1β reduces the rate of platelet aggregation in nonstressed August and WAG rats and elevates it in Wistar rats. Preliminary injection of interleukin-1β reduces the stress-induced changes in platelet aggregation in August and WAG rats; while in Wistar rats this effect is not observed.

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References

  1. S. S. Pertsov, V. M. Abramov, A. S. Sosnovskii,et al., Byull. Eksp. Biol. Med.,117, No. 3, 238–239 (1994).

    CAS  Google Scholar 

  2. S. S. Pertsov, T. S. Balashova, A. A. Kubatiev,et al.,,120, No. 9, 244–247 (1995).

    CAS  Google Scholar 

  3. K. V. Sudakov,Pat. Fiziol., No. 4, 86–93 (1992).

    Google Scholar 

  4. K. V. Sudakov,Byull. Eksp. Biol. Med.,123, No. 2, 124–130 (1997).

    Article  CAS  Google Scholar 

  5. M. Capelli-Bigazzi, K. G. Lamping, D. W. Nuno, and D. G. Harrison,Am. J. Physiol.,259, H1161-H1170 (1990).

    Google Scholar 

  6. A. J. Chovergonzalez, M. S. Harbuz, and S. L. Lightman,J. Neuroimmunol.,42, 155–160 (1993).

    Article  CAS  Google Scholar 

  7. J. I. Haft and Y. S. Arkel,Chest,70, 501–505 (1976).

    PubMed  CAS  Google Scholar 

  8. M. Irwin,Endocrinology,133, 1352–1360 (1993).

    Article  PubMed  CAS  Google Scholar 

  9. P. T. Larson, P. Hjemdahl, G. Olsson,et al., Clin. Sci.,76, 369–376 (1989).

    Google Scholar 

  10. G. Mastoracos, G. P. Chrousos, and J. S. Weber,J. Clin. Endocrinol. Metab.,77, 1690–1694 (1993).

    Article  Google Scholar 

  11. W. G. Mayhan,Brain Res.,545, 97–102 (1991).

    Article  PubMed  CAS  Google Scholar 

  12. M. Minami, Y. Kuraishi, T. Yamaguchi,et al., Neurosci. Lett.,123, 254–256 (1991).

    Article  PubMed  CAS  Google Scholar 

  13. J. Overmier, R. Murison,et al., Behav. Neural Biol.,46, 372–386 (1986).

    Article  PubMed  CAS  Google Scholar 

  14. C. Rougeot, C. Tiberghein, P. Minary, and F. Dray,J. Lipid Mediator,4, 45–60 (1991).

    CAS  Google Scholar 

  15. A. Saperstein, H. Brand, T. Audhya,et al., Endocrinology,130, 152–158 (1992).

    Article  PubMed  CAS  Google Scholar 

  16. A. S. Sosnovsky and A. A. Kubatiev,Stress Medicine,9, 207–214 (1993).

    Google Scholar 

  17. D. H. Zhou, A. W. Kusnecov, M. R. Shurin,et al., Endocrinology,133, 2523–2530 (1993).

    Article  PubMed  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow

    S. S. Pertsov, A. S. Sosnovskii, A. A. Kubatiev & G. V. Pirogova

Authors
  1. S. S. Pertsov
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  2. A. S. Sosnovskii
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  3. A. A. Kubatiev
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  4. G. V. Pirogova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 144–147, August, 1997

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Pertsov, S.S., Sosnovskii, A.S., Kubatiev, A.A. et al. Effect of interleukin-1β on platelet aggregation in August, Wistar, and WAG rats in acute emotional stress. Bull Exp Biol Med 124, 747–750 (1997). https://doi.org/10.1007/BF02445080

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  • DOI: https://doi.org/10.1007/BF02445080

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