Abstract
Lithium hydroxybutyrate (10 mg/kg daily for 10 days, intramuscularly) administered in the morning prevents reserpine-induced depression of the diurnal steroidogenesis in mice and the development of desynchronosis between circadian rhythms of serotonin in the brain and plasma corticosteroids. Evening injections result in the formation of phase-discordant 24-h periodicities, the mean values of the studied parameters being unaffected.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 7, pp. 101–105, July, 1997
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Zamoshchina, T.A., Saratikov, A.S. & Lishmanov, Y.B. Effect of lithium hydroxybutyrate on circadian rhythms of brain serotonin content and plasma corticosteroids in reserpine-treated mice. Bull Exp Biol Med 124, 709–712 (1997). https://doi.org/10.1007/BF02445069
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DOI: https://doi.org/10.1007/BF02445069