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Effect of sodium citrate on the rate of cholesterol esterification and on the formation of primary products of lipid peroxidation in human blood. Are these processes related?

  • Experimental Methods for Clinical Practice
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Abstract

In vitro experiments show that sodium citrate in a final concentration of 130 mM induces a 4- to 5-fold increase in the activity of lecithin-cholesterol acyltransferase. A parallel determination of the blood content of primary products of lipid peroxidation reveals a 20–30% decrease in diene and triene conjugates and lipid hydroperoxides.

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Authors and Affiliations

  1. Research Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg

    A. A. Nikiforova & A. A. Kuz'min

  2. Institute of Clinical Chemistry and Laboratory Diagnostics, Leipzig University, Germany

    W. Richter

Authors
  1. A. A. Nikiforova
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  2. A. A. Kuz'min
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  3. W. Richter
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 9, pp. 323–325, September, 1995

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Nikiforova, A.A., Kuz'min, A.A. & Richter, W. Effect of sodium citrate on the rate of cholesterol esterification and on the formation of primary products of lipid peroxidation in human blood. Are these processes related?. Bull Exp Biol Med 120, 962–964 (1995). https://doi.org/10.1007/BF02445031

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  • DOI: https://doi.org/10.1007/BF02445031

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