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Ultrastructure of renal-cell tumors induced in mice by 1,2-dimethylhydrazine

  • Oncology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Fifteen primary renal adenomas induced with 1,2-dimethylhydrazine in CBA mice and 3 passages of adenomas transplanted subcutaneously were examined by electron microscopy. A well-developed brush border was found in one primary adenoma, this being in line with histochemical data on the presence of markers of the proximal canaliculi epithelium in this tumor. In other tumors a reduced brush border (5 cases) and apical canaliculi (14 cases) were revealed, which are typical of the proximal canaliculi epithelium. The ultrastructure of the types of adenoma cells is described. Atypical tumor cells with intracellular lumina were found in transplanted adenomas

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Authors and Affiliations

  1. Department of Carcinogens, Research Institute of Carcinogenesis, Cancer Research Center, Russian Academy of Medical Sciences, Moscow

    V. F. Kondalenko, G. Yu. Chemeris & V. S. Turusov

Authors
  1. V. F. Kondalenko
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  2. G. Yu. Chemeris
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  3. V. S. Turusov
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 9, pp. 286–290, September, 1995

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Kondalenko, V.F., Chemeris, G.Y. & Turusov, V.S. Ultrastructure of renal-cell tumors induced in mice by 1,2-dimethylhydrazine. Bull Exp Biol Med 120, 925–929 (1995). https://doi.org/10.1007/BF02445019

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  • DOI: https://doi.org/10.1007/BF02445019

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