Bulletin of Experimental Biology and Medicine

, Volume 120, Issue 4, pp 1073–1076 | Cite as

Proton NMR relaxation of the nonaqueous component of human blood serum

  • M. G. Gangardt
  • N. F. Karyakina
  • A. S. Pavlov
  • E. A. Papish


Proton magnetic resonance relaxation was experimentally studied in native blood serum in groups of healthy subjects and patients with malignant tumors. Although the longitudinal relaxation timeT 1 of the aqueous component in these groups was found to differ reliably, the longitudinal relaxation time of nonexchanging or slowly exchanging protons in these samples within the attained range of accuracy was virtually the same. Moreover, it was revealed that the amplitude of the “nonaqueous component” of blood serum correlates with the protein concentration in the samples.

Key Words

NMR relaxation blood serum proton exchange malignant growth 


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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • M. G. Gangardt
    • 1
  • N. F. Karyakina
    • 1
  • A. S. Pavlov
    • 1
  • E. A. Papish
    • 1
  1. 1.Department of Clinical RadiologyRussian Medical Academy for Postgraduate TrainingMoscow

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