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Effect of native venom of red cobra (Naja pallida) on morphological and rheological properties of erythrocytes

  • Experimental Methods in Clinical Practice
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of native venom of red (spitting) cobra (Naja pallida) on human erythrocytes is studied using the methods of electron microscopy and filtration through Millipore filters. Morphological analysis reveals marked transformation of discoid erythrocytes to echinocytes. More prolonged contact of the blood with the venom impairs the deformability of erythrocytes and induces hemolysis and the sludge syndrome. The results indicate a potent cytotoxic effect of native venom of red cobra.

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Authors and Affiliations

  1. Department of Faculty Surgery, Russian State Medical University, Moscow

    E. B. Petukhov, N. P. Aleksandrova, A. V. Savushkin, N. N. Kvitko & D. B. Vasil'ev

Authors
  1. E. B. Petukhov
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  2. N. P. Aleksandrova
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  3. A. V. Savushkin
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  4. N. N. Kvitko
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  5. D. B. Vasil'ev
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 10, pp. 425–427, October, 1995

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Petukhov, E.B., Aleksandrova, N.P., Savushkin, A.V. et al. Effect of native venom of red cobra (Naja pallida) on morphological and rheological properties of erythrocytes. Bull Exp Biol Med 120, 1055–1057 (1995). https://doi.org/10.1007/BF02444984

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  • DOI: https://doi.org/10.1007/BF02444984

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