The quaternary ammonium salt of conidine oligomer 25 hastens healing of skin wounds in rats
Collagen sponges and films containing a synthetic polycation, the quaternary ammonium salt of conidine oligomer 25, stimulate the repair processes when applied to a wound, accelerating the final epithelialization of skin wounds. The effect of the drug manifests itself mainly during the proliferation and cicatrization stages by speeding up replication and transcription in the fibroblasts and producing intercellular matrix components.
Key Wordsskin repair polycation sponges films autoradiography histochemistry
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