Bulletin of Experimental Biology and Medicine

, Volume 120, Issue 4, pp 1019–1020 | Cite as

Vertical motor activity is inhibited in mice by lower doses of psychotropic drugs than horizontal activity

  • I. P. Lapin
  • R. A. Khaunina
  • S. M. Mirzaev
Pharmacology and Toxicology


This study of 19 psychotropic drugs for their effect on motor activity of mice showed that all types of drugs (tranquilizers, sedatives, neuroleptics, antidepressants, and anticonvulsants) inhibit vertical activity to a greater extent than horizontal activity.

Key Words

vertical activity horizontal activity mice inhibitory action of drugs 


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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • I. P. Lapin
    • 1
  • R. A. Khaunina
    • 1
  • S. M. Mirzaev
    • 1
  1. 1.V. M. Bekhterev Institute of PsychoneurologySt. Petersburg

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