Abstract
The effect of intravenous administration of oxypine (Mexidol), an antioxidant of the 3-oxypyridine group, on hydration of rabbit tissues in allergy is studied. It is found that oxypine reduces edema of the “shock” organs: trachea, lungs, esophagus, duodenum, and spleen, attenuates sensitization and anaphylactic edema, and diminishes the fluid redistribution in tissues that is characteristic of allergy.
Similar content being viewed by others
References
E. S. Wentzel,Probability Theory [Russian translation from German], Moscow (1969).
L. D. Smirnov and K. M. Dyumaev, in:Bulletin All-Union Center for Safety of Biologically Active Substances [in Russian], Moscow (1992), p. 9.
G. N. Chetverikov,Allergic Reactions in Experimental and Clinical Practice [in Russian], Moscow (1986), pp. 6–24.
R. Catheact,Med. Hypotheses,21, Nolo 3, 307–321 (1986).
S. Seldon, R. Weindruch, and R. Walfrod,Free Radicals, Aging, and Degenerative Diseases, New York (1986), pp. 427–456.
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, Nulo 7, pp. 84–86, July, 1995
Rights and permissions
About this article
Cite this article
Bazanov, G.A. Effect of oxypine on edema of rabbit tissues in allergy. Bull Exp Biol Med 120, 730–732 (1995). https://doi.org/10.1007/BF02444674
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02444674