Bulletin of Experimental Biology and Medicine

, Volume 118, Issue 5, pp 1220–1225 | Cite as

Changes in the morphofunctional state of the thyroid gland under the combined influence of hypokinesia and hypothermia

  • N. S. Khoch
  • V. V. Lopukhova
  • A. D. Gratsianova
Morpholocy and Pathomorphology
  • 19 Downloads

Abstract

It is shown that under the influence of a 5-day hypokinesia and hypothermia applied as individual and combined factors the rat thyroid gland develops a compromised response, displaying elements of a reaction to both hypokinesia and hypothermia. Some follicles in the central zone of the thyroid were in substantial functional tension, while in other areas of the organ synthesis and secretion were markedly suppressed. A severe deficiency of thyroid hormones in the organism leads to profound metabolic changes, impairments of thermoregulation mechanisms, and even death of some animals toward the end of the study.

Key Words

thyroid gland hypokinesia hypothermia 

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References

  1. 1.
    G. G. Avtandilov,Introduction to Quantitative Pathological Morphology [in Russian], Moscow (1980).Google Scholar
  2. 2.
    B. V. Aleshin and V. N. Gubskii,The Hypothalamus and Thyroid Gland [in Russian], Moscow (1983).Google Scholar
  3. 3.
    I. A. Arshavskii,Nervous and Endocrine Mechanisms of Stress [in Russian], Kishinev (1980), pp. 3–24.Google Scholar
  4. 4.
    A. A. Voitkevich and V. S. Zenzerov,Arkh. Anat., No, 10, 28–25 (1968).Google Scholar
  5. 5.
    E. A. Kovalevskii and N. N. Gurovskii, Hypokinesia [in Russian], Moscow (1980).Google Scholar
  6. 6.
    B. E. Mel'nik and M. S. Kakhana,Biomedical Forms of Stress [in Russian], Kishinev (1981).Google Scholar
  7. 7.
    M. R. Mogendovich,Experimental Studies on Physiology, Biochemistry, and Pharmacology [in Russian], Vol. 3, Perm' (1961).Google Scholar
  8. 8.
    V. K. Preobrazhenskii, M. I. Agadzhapov, and S. V. Alisievich,The Thermoregulatory System during the Adaptation of the Organism to Environmental Factors [in Russian], Vol. 1, Novosibirsk (1990), p. 125.Google Scholar
  9. 9.
    V. V. Portugalov and A. V. Gorbunova,Nineteenth–Twentieth Century Annals Published to Mark the 70th Birthday of Academician A. D. Zurabashvilli [in Russian], Tbilisi (1974), pp. 342–347.Google Scholar
  10. 10.
    A. I. Robu,Interaction between Endocrine Complexes in Stress [in Russian], Kishinev (1982).Google Scholar
  11. 11.
    V. I. Sobolev, Keita Bengali, L. I. Apostolaka, and G. I. Chirva,Thermoregulatory System during the Adaptation of the Organism to Environmental Factors [in Russian], Vol. 1, Novosibirsk (1990), p. 75.Google Scholar
  12. 12.
    A. V. Tkachev and I. V. Berul',Neuroendocrine Correlations [in Russian], Vladivostok (1978), pp. 52–64.Google Scholar
  13. 13.
    E. Ya. Tkachenko,Physiology of Adaptation to Cold and to Mountains and Subarctic Conditions [in Russian], Novosibirsk (1975), pp. 6–9.Google Scholar
  14. 14.
    I. B. Khavin,The Thyroid Gland [in Russian], Moscow (1967).Google Scholar
  15. 15.
    F. I. Furdui, S. Kh. Khaidarliu, and L. M. Mamalyga,Combined Influence of Extreme Factors on the Organism [in Russian], Kishinev (1985).Google Scholar

Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • N. S. Khoch
    • 1
    • 2
  • V. V. Lopukhova
    • 1
    • 2
  • A. D. Gratsianova
    • 1
    • 2
  1. 1.Department of Human Anatomy, Physiology, and HygieneSiate Pedagogical InstituteTomsk
  2. 2.Laboratory of Radiation Physiology, Institute of Biology and BiophysicsTomsk State IniversityTomskUSSR

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