Bulletin of Experimental Biology and Medicine

, Volume 118, Issue 5, pp 1220–1225 | Cite as

Changes in the morphofunctional state of the thyroid gland under the combined influence of hypokinesia and hypothermia

  • N. S. Khoch
  • V. V. Lopukhova
  • A. D. Gratsianova
Morpholocy and Pathomorphology


It is shown that under the influence of a 5-day hypokinesia and hypothermia applied as individual and combined factors the rat thyroid gland develops a compromised response, displaying elements of a reaction to both hypokinesia and hypothermia. Some follicles in the central zone of the thyroid were in substantial functional tension, while in other areas of the organ synthesis and secretion were markedly suppressed. A severe deficiency of thyroid hormones in the organism leads to profound metabolic changes, impairments of thermoregulation mechanisms, and even death of some animals toward the end of the study.

Key Words

thyroid gland hypokinesia hypothermia 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • N. S. Khoch
    • 1
    • 2
  • V. V. Lopukhova
    • 1
    • 2
  • A. D. Gratsianova
    • 1
    • 2
  1. 1.Department of Human Anatomy, Physiology, and HygieneSiate Pedagogical InstituteTomsk
  2. 2.Laboratory of Radiation Physiology, Institute of Biology and BiophysicsTomsk State IniversityTomskUSSR

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