Abstract
A W/SSM strain of rats with hereditary hypertrophic cardiomyopathy has been created by inbreeding Wistar rats selected for an increased, sensitivity to the cataractogenic effect of high doses of galactose. It is shown that myocardial hypertrophy attended by a diffuse stroma collagenization, focal sclerotic changes, and signs of, chronic heart failure spontaneously develops in these animals.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 8, pp. 203–207, August, 1994
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Salganik, R.I., Solov'eva, N.A., Nepomnyashchikh, L.M. et al. Morphological manifestations of hereditary hypertrophic cardiomyopathy in W/SSM rats. Bull Exp Biol Med 118, 900–904 (1994). https://doi.org/10.1007/BF02444460
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DOI: https://doi.org/10.1007/BF02444460