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Rheumatoid factors of the blood and cerebrospinal fluid in patients with a complicated spinal injury

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The levels of rheumatoid factors (RF) of IgM-RF and IgG-RF classes were measured by enzyme immunoassay (EIA) in the sera of patients with spinal injuries. Analysis showed that 46% of patients with spinal injuries were seropositive for IgG-RF-and 40% for IgM-RF; no IgG-RF was detected in the cerebrospinal fluid (CSF), whereas the IgM-RF content was 37.6 μg/ml. Results of RF measurements in the sera make it possible to qualify the systemic involvement of the body in the late period of a spinal injury as a rheumatic disease. The findings point to the presence of independent mechanisms of immune control in the CSF.

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Authors and Affiliations

  1. Department of Traumatology, Orthopedics, and Military Surgery, I. M. Sechenov Medical Academy, Moscow

    N. V. Petrova, G. S. Yumashev, V. A. Aleshkin & A. M. Ponomareva

Authors
  1. N. V. Petrova
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  2. G. S. Yumashev
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  3. V. A. Aleshkin
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  4. A. M. Ponomareva
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 8, pp. 174–176, August, 1994

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Petrova, N.V., Yumashev, G.S., Aleshkin, V.A. et al. Rheumatoid factors of the blood and cerebrospinal fluid in patients with a complicated spinal injury. Bull Exp Biol Med 118, 868–870 (1994). https://doi.org/10.1007/BF02444452

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  • DOI: https://doi.org/10.1007/BF02444452

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