Abstract
A potent inhibition of leukocyte migration, as high as 98%, was observed in superacute and acute forms and exacerbation of the chronic form of African swine fever. In an asymptomatic infection the inhibition is no more than 30%. Inhibition of the migration of porcine leukocytes infected in a cell culture was 73 to 90% after infection with four virulent strains and 15 to 36% after infection with two attenuated strains. The data onin vitro andin vivo leukocyte sensitization in African swine fever are indicative of a correlation between the severity of the pathogenetic picture of the disease and the degree of delayed-type hypersensitivity.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 8, pp. 168–170, August, 1994
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Shubina, N.G., Kolontsov, A.A. & Makarov, V.V. Delayed-type hypersensitivity and the pathogenesis of viral hemorrhagic fever (African swine fever). Bull Exp Biol Med 118, 862–864 (1994). https://doi.org/10.1007/BF02444450
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DOI: https://doi.org/10.1007/BF02444450