Bulletin of Experimental Biology and Medicine

, Volume 118, Issue 2, pp 824–827 | Cite as

Effects of supplementing the rat diet with selenium on the efficiency of essential linoleic acid metabolism

  • S. N. Kulakova
  • Z. V. Karagodina
  • M. M. Levachev
  • M. N. Volgarev
Biophysics and Biochemistry


Examination of the fatty-acid composition of lipids contained in the liver, spleen, blood plasma, aggregated lymphatic follicles of the small intestine, and mesenteric lymph nodes of rats fed diets supplemented with selenium revealed an appreciable effect of this element on the efficiency with which linoleic acid was metabolized to arachidonic acid, which was reflected in an increased 20:4/18:2 ratio. In contrast, Se was found to have little or no effect on levels of lipid peroxidation products in tissues and blood serum.

Key Words

selenium in rat diet lipid peroxidation linoleic acid metabolism 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • S. N. Kulakova
    • 1
  • Z. V. Karagodina
    • 1
  • M. M. Levachev
    • 1
  • M. N. Volgarev
    • 1
  1. 1.Institute of NutritionRussian Academy of Medical SciencesMoscow

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