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Functional activity of human leukocytes exposed to a hypotonic medium

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

This study, in which zymosan-stimulated luminol-dependent chemiluminescence of leukocytes was used to examine the osmotic resistance and functional activity of peripheral blood leukocytes from 23 patients with purulent septic lesions and 11 healthy donors before and after exposure of these cells to a hypotonic medium (0.45% NaCl), showed that this medium stimulated their spontaneous chemiluminescence while reducting their reserve capacities. The effects of the hypotonic medium on cells from the patients were more strongly marked.

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References

  1. L. S. Bondarev, I. A. Zaitsev, V. N. Zhidkikh,et al., Lab. Delo, No 7, 29–31 (1990).

    PubMed  Google Scholar 

  2. N. V. Kuchkina, S. N. Orlov, N. I. Pokudin,et al., Byull. Eksp. Biol. Med.,115, No 4, 360–362 (1993).

    Article  CAS  Google Scholar 

  3. V. A. Chernov and E. N. Chukhareva,Acquired Immunodeficiency States: Clinical and Experimental Studies [in Russian], Chelyabinsk (1990).

  4. Y. Aida and M. J. Pabs,J. Immunol.,145, No 9, 3017–3018 (1990).

    PubMed  CAS  Google Scholar 

  5. M. Bonnet, T. Matsumoto, T. Husson,et al., Arch. Int. Physiol.,95, No 4, 51 (1987).

    Google Scholar 

  6. B. Descamps-Latscha, A. T. Nguyen, R. M. Golub,et al.,Ann. Immunol.,133, No 3, 349–364.

  7. S. Grinstein and J. Foskett,Ann. Rev. Physiol.,52, 399–414 (1990).

    Article  CAS  Google Scholar 

  8. C. W. Parker,Amer. Rev. Respir. Disease,143, No 3, Pt. 2, 559–560 (1991).

    Google Scholar 

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 7, pp. 93–94, July, 1994

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Gindich, L.A. Functional activity of human leukocytes exposed to a hypotonic medium. Bull Exp Biol Med 118, 779–780 (1994). https://doi.org/10.1007/BF02444385

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  • DOI: https://doi.org/10.1007/BF02444385

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