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Bulletin of Experimental Biology and Medicine

, Volume 118, Issue 1, pp 728–730 | Cite as

Effect of substance P on the content of catecholamines and on the enzymes of their synthesis in the brain of chronically alcoholized rats

  • I. P. Anokhina
  • A. G. Veretinskaya
  • A. A. Rodionov
  • N. A. Khristolyubova
Pharmacology and Toxicology
  • 18 Downloads

Abstract

The effect of a single administration of the endogenous peptide substance P on the content of dopamine (DA), and norepinephrine (NE), and on the activity of tyrosine hydroxylase (TH) and dopamine β-hydroxylase (D-β-H) is studied in the hypothalamus and midbrain of rats after a 6-month alcoholization.

Key Words

substance P dopamine β-hydroxylase tyrosine hydroxylase catecholamines alcohol 

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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • I. P. Anokhina
    • 1
  • A. G. Veretinskaya
    • 1
  • A. A. Rodionov
    • 1
  • N. A. Khristolyubova
    • 1
  1. 1.Institute of Medico-Biological Problems of Narcology, State Research Center of NarcologyMinistry of Health of the Russian FederationMoscow

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