Abstract
Vesiculation of the plasmalemma followed by fragmentation to microvesicles and formation of microspherocytes are shown to be the main phenomena during aging in rat erythrocytes. In human erythrocytes microvesiculation from the apexes of echinocyte spicules and hemolysis in echinocytes II–IV are predominant. Hemolysis, vesiculation, and microvesiculation are observed in rabbit, and hemolysis and microvesiculation in canine erythrocytes. An increased level of free fatty acids (about 30% per hour) in human and rat erythrocytes is also detected.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 5, pp. 555–558, May, 1994
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Sorokovoi, V.I., Mochenova, N.N. & Nikitina, G.M. Ultrastructure of erythrocytes during calcium-inducedin vitro aging. Bull Exp Biol Med 117, 558–561 (1994). https://doi.org/10.1007/BF02444317
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DOI: https://doi.org/10.1007/BF02444317