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Effect of cytochromec on the necrosis zone in transitory myocardial ischemia

  • Pharmacology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The cardioprotector effect of cytochromec during a 15-min complete blocking of the anterior descending branch of the left coronary artery was studied in rat experiments. Cytochromec in a dose of 20 mg/kg was found to noticeably reduce the necrosis zone 4 h after transitory ischemia. The protective effect of a single injection of cytochromec was virtually undetectable after 72, h, this pointing to the need for a course of treatment.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No, 4, pp. 439–440, April, 1994

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Gatsura, V.V., Imatdieva, R.M. Effect of cytochromec on the necrosis zone in transitory myocardial ischemia. Bull Exp Biol Med 117, 438–440 (1994). https://doi.org/10.1007/BF02444205

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  • DOI: https://doi.org/10.1007/BF02444205

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