Bulletin of Experimental Biology and Medicine

, Volume 117, Issue 4, pp 421–423 | Cite as

Reproduction of the primary rhythms of excitation in cardiac activity of neonatal rat pups

  • S. V. Kuznetsov


It is shown that during activation of the central N-cholinergic systems, the cardiac pacemaker elements in neonatal rat pups are capable of switching between discontinuous rhythmic activity and the generation of periodic excitation, when complexes of cardiac contractions at a rate of 60 min−1 alternate with 5–15-sec intervals of rest. This type of activity is close to the primary rhythms of excitation, which are characteristic of the activity of excitatory structures during the early phylo- and ontogenetic stages of development.

Key Words

ontogenesis cardiac rhythm cholinomimetics 


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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • S. V. Kuznetsov
    • 1
  1. 1.I. M. Sechenov Institute of Evolutionary Physiology and BiochemistryRussian Academy of SciencesSt. Petersburg

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