Skip to main content
Log in

The possibilities of clinical transplantation of the testis as an organ and tissue

  • Transplantation of Human Fetal Tissue
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In our century the transplantation of testes as replacement therapy and the method of rejuvenation of the organism have elicited great interest. The history of the procedure started with the transplantation of testes from adult men; then came transplantation of fetal testes (with the description of various new surgical methods), followed by experiments in the transplantation of human fetal testicular tissue, including tissue cultures, and treatment with lyophilizates from animal testes. The transplantation of the fetal testis as a tissue and as cell cultures and treatment with testicular tissue extracts may effectively stimulate the regeneration of the testis proper in hypogonadism of various etiology, including incurable hypergonadotropic forms.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. I. A. Brodskii,Zh. Psikhol., Nevrol. Psikhiatr. No 3, 107–114 (1923).

    Google Scholar 

  2. V. I. Vasil'ev,Transplantation of the Testis with the Arteriovenous Pedicle in Primary Hypogonadism, Dissertation [in Russian], Moscow (1983).

  3. P. P. Viktorov,Brown-Sequard's Method of Subcutaneous Injections and Its Significance for the Treatment of Neurological Patients, Senile Dementia, and Tuberculosis [in Russian], Kushnerov Press, Moscow (1891).

    Google Scholar 

  4. L. G. Vol'fenzon,Byull. Eksp. Biol. Med.,3, No 6, 675–678 (1937).

    Google Scholar 

  5. Problems of Andrology and Testis Transplantation. Collection of Articles [in Russian], Moscow (1974), pp. 5–11.

  6. S. A. Voronov and G. Aleksandresku,Transplanting Testes from Monkey to Man [in Russian], Moscow-Leningrad (1930).

  7. T. E. Gnilorybov,Khirurgiya, No 1, 73–78 (1948).

    Google Scholar 

  8. T. E. Gnilorybov and V. Z. Nekhvyadovich,Urol. Nefrol., No 2, 50–52 (1965).

    Google Scholar 

  9. D. L. Gorbatyuk and Zh. L. Petrosyan, in:Transplantation of Endocrine Organs in Clinical Practice and Experiment [in Russian], Moscow (1972), pp. 50–52.

  10. D. L. Gorbatyuk and S. S. Raitsina,Klin. Khir. No 12, 12–14 (1980).

    Google Scholar 

  11. O. A. Gotsiridze,Problems of Microsurgery [in Russian], Moscow (1981), pp. 81–83.

  12. Guaze,Extended Life via the Brown-Sequard Method [in Russian], Moscow (1907).

  13. E. S. Dendeberov,Cultural Allotransplantation of Neonatal Endocrinocytes of Testes, Dissertation [in Russian], Moscow (1993).

  14. P. A. Dyban,Arkh. Anat.,99, No 11, 75–80 (1990).

    PubMed  CAS  Google Scholar 

  15. M. M. Zavadovskii,Sex and the Development of Its Characters (Analysis of Morphogenesis in Animals) [in Russian], Moscow (1922).

  16. S. L. Znoiko, A. E. Chagai, V. N. Mitashev,et al., Izv. Akad. Nauk SSSR, Ser. Biol., No 3, 346–357 (1993).

    Google Scholar 

  17. D. V. Zybin, A. S. Prigoda, V. I. Vasil'ev,et al., A Method of Treating Patients with Male Sexual Dysfunction by the Transplantation Technique [in Russian], Pat. No92-015909/14 from 12.15.92.

  18. V. T. Karpukhin,Problems of Urology [in Russian], Zaporozh'e 91964), pp. 57–60.

  19. V. T. Karpukhin, I. S. Kolpakov, and V. V. Robustov,Transplantation of Organs and Tissues [in Russian], Gorki (1970), pp. 170–171.

  20. I. D. Kirpatovskii,Surgical Correction of Endocrine Impotence [in Russian], Moscow (1986), pp. 5–13, 155–156.

  21. I. D. Kirpatovskii and D. L. Gorbatyuk,Khirurgiya, No 6, 103–106 (1990).

    Google Scholar 

  22. M. E. Basmadzhyan,The Technique of Manufacturing Cultures of Embryonal Interstitial Endocrinocytes of Human Testis. Procedural Guidelines [in Russian], Erevan (1990).

  23. A. A. Nemilov,The Basis of the Theory and Practice of Transplanting Tissues and Organs [in Russian], Leningrad (1940).

  24. Zh. L. Petrosyan and S. S. Raitsina, in:Spermatogensis and Its Regulation [in Russian], Moscow (1983), pp. 141–160.

  25. V. E. Predtechenskii,Clinical Observations on the Effect of Brown-Sequard Fluid [in Russian], Moscow (1894).

  26. S. S. Raitsina and I. S. Kazakova,Reports of the Third All-Union Conference on Transplantation of Organs and Tissues [in Russian], Erevan (1963), pp. 428–429.

  27. G. E. Rumyantsev,On the Theoretical Basis of Tissue Therapy [in Russian], Rostov (1953).

  28. I. S. Turchin, S. K. Kobyakov, O. P. Potikha,et al., A Method of Treatment of Male Hypogonadism [in Russian], Pat. No 4668891/00-14 from 03.30.89.

  29. A. A. Ugarov,Byull. Eksp. Biol. Med.,5, No 6, 714–716 (1938).

    Google Scholar 

  30. Equipment of a Bank for Autologous Therapy. German (Pat.) No 3839836, published 05.31.90, No 22.

  31. A. I. Filatov, Yu. V. Beringer, and G. V. Golovin,Transplantation and Replacement of Tissues and Organs [in Russian], Leningrad (1960).

  32. Anonymous,JAMA,58, 484 (1912).

  33. S. E. Attaran, C. V. Hodges, L. S. Crary,et al., J. Urology,95, No 3, 387–389 (1966).

    CAS  Google Scholar 

  34. E. M. Barksdale, Jr., T. G. McGenis, and P. K. Donahoe,J. Pediatr. Surg.,26, No 8, 886–892 (1991).

    Article  PubMed  Google Scholar 

  35. M. Benahmed,Ann. Endocrinol.,53, No 2, 12 (1992).

    Google Scholar 

  36. A. A. Berthold,Arch. Anat., Physiol. Wessenschaft. Med.,16, 42–46 (1849).

    Google Scholar 

  37. P. F. Boyle, M. Fox, and D. Slater,Brit. J. Urol.,47, 891–898 (1976).

    Google Scholar 

  38. A. C. Buck,Amer. J. Anat.,113, No 2, 189–213 (1963).

    Article  PubMed  CAS  Google Scholar 

  39. W. von Camerer,Cytobiologische Revue, No 2, 12–16 (1978).

    Google Scholar 

  40. Y. Clermont and A. Mauger,Cell Tiss. Kinet., No 7, 165–172 (1974).

    CAS  Google Scholar 

  41. G. F. Corners,Rejuvenation. How Steinach Makes People Young, New York (1923).

  42. L. A. Feig, A. R. Bellvue, N. Horbach-Erickson,et al., Proc. Nat. Acad. Sci. USA (Wash.),77, 4774–4778 (1980).

    Article  CAS  Google Scholar 

  43. M. Fox, P. F. Boyle, and J. C. Hammonds,Brit. J. Urol.,45, 696–701 (1973).

    PubMed  CAS  Google Scholar 

  44. A. C. Gianoli,Cytobiologische Revue 1 (1977), pp. 30–34.

    Google Scholar 

  45. W. Goody,Proc. R. Soc. Med.,57, 189 (1964).

    Google Scholar 

  46. M. T. Hochereau-de Reviers and M. Courot,Ann. Biol. anim. Biochem. Biophys.,18, 573–583 (1978).

    CAS  Google Scholar 

  47. M. T. Hochereau-de Reviers, M. C. Viguier-Martinez, and C. Perrean,Andrologia,14, 297–305 (1982).

    Article  PubMed  CAS  Google Scholar 

  48. Y. M. Hu,Chung. Hua. Wai. Ko. Tsa. Chih.,28, No 8, 484–486 (1990).

    Google Scholar 

  49. J. C. Hutson,J. Reprod. Immunol.,23, No 1, 63–72 (1993).

    Article  PubMed  CAS  Google Scholar 

  50. W. Kearns,Ann. Surg.,114, 886 (1941).

    PubMed  CAS  Google Scholar 

  51. C. D. Kochakian,NIDA. Res. Monogr.,102, 29–59 (1990).

    PubMed  CAS  Google Scholar 

  52. A. D. Lander, D. K. Fujii, D. Gospodarowicz,et al., J. Cell Biol.,94, 574–585 (1982).

    Article  PubMed  CAS  Google Scholar 

  53. J. Larkin,Am. J. Anat.,106, No 1, 75–87 (1960).

    Article  Google Scholar 

  54. S. Lee, K. Tung, and M. Orloff,Transplant. Proc.,3, 586–590 (1971).

    PubMed  CAS  Google Scholar 

  55. T. Linn, D. Romann, S. Voges,et al.,,24, 998 (1992).

    PubMed  CAS  Google Scholar 

  56. W. Nikolowski,Behandlung Mannlicher Potenzstorungen. Therapie-Woche, Karsruhe, Kongre-Bausgabe (1956), pp. 604–608.

    Google Scholar 

  57. M. Rashedi, R. Maraund, M. Audine,et al., C. R. Soc. Seances, Soc. Biol. Fil.,185, No 4, 211–217 (1991).

    CAS  Google Scholar 

  58. Regulation of Testicular Function: Signaling Molecules and Cell-Cell Communication, Eds. L. L. Ewing and R. Robire, New York (1989), p. XI.

  59. S. Sainio-Pollanen, P. Pollanen, and B. P. Setchell,J. Reprod. Immunol.,20, No 1, 59–72 (1991).

    Article  PubMed  CAS  Google Scholar 

  60. F. Schmid,Zell-Therapie-ein Schritt in die Zukunft der Medizin, Stuttgart (1992), p. 238.

  61. S. J. Silber,Fertil. Steril.,30, 181 (1978).

    PubMed  CAS  Google Scholar 

  62. R. Z. Sokol, B. S. Steiner, M. Bustilloet al., Fertil. Steril.,49, 865–870 (1988).

    PubMed  CAS  Google Scholar 

  63. R. F. Spark,The Infertile Man (1988), pp. 303–332.

  64. M. B. Statter, R. P. Foglia, D. E. Parks,et al., J. Urol.,139, 204–210 (1988).

    PubMed  CAS  Google Scholar 

  65. M. B. Statter, K. J. Fahrner, and E. M. Barksdale,Transplantation,47, 651–660 (1989).

    PubMed  CAS  Google Scholar 

  66. J. Tai, H. W. Johnson, and W. J. Tze,,47, No 6, 1087–1089 (1989).

    PubMed  CAS  Google Scholar 

  67. J. Tai, W. J. Tze, S. Yip,et al., Transplant. Proc.,24, No 6, 2917–2919 (1992).

    PubMed  CAS  Google Scholar 

  68. C. D. Turner,Amer. J. Anat.,63, 101–159 (1938).

    Google Scholar 

  69. S. voronoff,Grefft Testiculaires, Paris (1923).

  70. K. B. Whittington, S. S. Solomon, Z. N. Lu,et al., Endocrinology,128, No 6, 2671–2677 (1991).

    Article  PubMed  CAS  Google Scholar 

  71. R. G. Williams,Amer. J. Anat.,86, 343 (1950).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 4, pp. 400–404, April, 1994

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bozhedomov, V.A., Sukhikh, G.T. & Molnar, E.M. The possibilities of clinical transplantation of the testis as an organ and tissue. Bull Exp Biol Med 117, 400–404 (1994). https://doi.org/10.1007/BF02444196

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02444196

Key Words

Navigation