Abstract
Experiments on adult (5–7 months old) and old (28–30 months old) male rats reveal that ACTH induces a hyperpolarization of the plasma membrane of adrenocorticocytes from the fasciculate zone in both age groups of animals 24 hours after a single administration of the hormone. Actinomycin D, an inhibitor of protein synthesis, prevents the development of hyperpolarization.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, № 3, pp. 302–303, March, 1994
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Gorban, E.N. Interrelationship between the membrane potential of adrenocorticocytes and functional activity of the adrenal glands in adult and old rats. Bull Exp Biol Med 117, 305–307 (1994). https://doi.org/10.1007/BF02444172
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DOI: https://doi.org/10.1007/BF02444172