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On the mechanism of specific inhibition of stimulated chemiluminescence of polymorphonuclear leukocytes in allergic processes

  • Allergology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Luminol-dependent chemiluminescence of polymorphonuclear leukocytes stimulated by barium sulfate is studied in blood samples preincubated with a specific allergen in experimental allergic processes. Specific inhibition of chemiluminescence is observed in blood samples obtained from sensitized animals. The degree of inhibition depends on the nature of sensitization and the stage of the allergic process and is related to myeloperoxidase inhibition.

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Authors and Affiliations

  1. Medico-Biological Department, Russian State Medical University, Moscow

    V. I. Pytskii (Chair of General Pathology) & O. Yu. Filatov

Authors
  1. V. I. Pytskii
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  2. O. Yu. Filatov
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, № 3, pp. 299–301, March, 1994

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Pytskii, V.I., Filatov, O.Y. On the mechanism of specific inhibition of stimulated chemiluminescence of polymorphonuclear leukocytes in allergic processes. Bull Exp Biol Med 117, 302–304 (1994). https://doi.org/10.1007/BF02444171

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  • DOI: https://doi.org/10.1007/BF02444171

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