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The pharmacokinetics of (125I) 3-deoxy-3-iodine glucose on experimental tumor modelsin Vivo

  • Oncology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The dynamics of125I distribution is studied in rats with induced tumors of the prostate and mammary gland for intravenous administration of125I-3D-G. It is found that 80% of the activity is eliminated in the first 24 hours. A relatively high level of125I accumulation is found in necrotically altered regions of the tumor.

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Authors and Affiliations

  1. Moscow Research Institute of Diagnostics and Surgery, Russian Ministry of Health, Moscow

    V. K. Bozhenko, E. V. Khmelevskii, A. M. Shishkin, V. N. Vasil'ev, A. G. Zakharov & V. I. Kiselev

  2. State Institute of Physico-Technical Problems, Russian Academy of Sciences, Moscow

    V. K. Bozhenko, E. V. Khmelevskii, A. M. Shishkin, V. N. Vasil'ev, A. G. Zakharov & V. I. Kiselev

Authors
  1. V. K. Bozhenko
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  2. E. V. Khmelevskii
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  3. A. M. Shishkin
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  4. V. N. Vasil'ev
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  5. A. G. Zakharov
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  6. V. I. Kiselev
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, № 3, pp. 294–295, March, 1994.

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Bozhenko, V.K., Khmelevskii, E.V., Shishkin, A.M. et al. The pharmacokinetics of (125I) 3-deoxy-3-iodine glucose on experimental tumor modelsin Vivo . Bull Exp Biol Med 117, 297–299 (1994). https://doi.org/10.1007/BF02444169

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  • DOI: https://doi.org/10.1007/BF02444169

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