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Dissociation of E∶T conjugates upon activation of human natural killers by factors acting at the “lethal blow” stage

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

It is demonstrated that in the presence of human recombinant γ-interferon and C-reactive protein the activity of natural killers increases 9–43%, whereas the number of effector:target cell conjugates formed at the stage of recognizing and binding of target cells decreases 14–80%. There is a weak positive correlation (ρ=0.35) between the activity of natural killers and the number of effector:target cell conjugates.

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Authors and Affiliations

  1. Laboratory of Immunochemistry and Laboratory of Natural Immunity, N. F. Gamaleya Institute of Epidemiology and Microbiology, Moscow

    S. B. Cheknev, D. V. Kuyavskaya, S. Zh. Toksambaeva, E. B. Mysyakin & A. Ya. Kul'berg

Authors
  1. S. B. Cheknev
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  2. D. V. Kuyavskaya
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  3. S. Zh. Toksambaeva
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  4. E. B. Mysyakin
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  5. A. Ya. Kul'berg
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 3, pp. 280–285, March, 1994

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Cheknev, S.B., Kuyavskaya, D.V., Toksambaeva, S.Z. et al. Dissociation of E∶T conjugates upon activation of human natural killers by factors acting at the “lethal blow” stage. Bull Exp Biol Med 117, 283–287 (1994). https://doi.org/10.1007/BF02444164

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  • DOI: https://doi.org/10.1007/BF02444164

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