Bulletin of Experimental Biology and Medicine

, Volume 117, Issue 2, pp 197–200 | Cite as

Equipment and technique forIn vitro modeling of thrombogenesis

  • I. P. Stepanova
  • S. P. Domogatskii


The device is a centrally oriented rotary magnetic disk producing a certain clearance between the rotary part and the collagen-coated bottom of a standard multiwell plate. Regulation of the speed of rotation makes it possible to reproduce the high shear rates characteristic for large elastic arteries.

Key Words

collagen thrombogenesis model of thrombogenesis 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    V. L. Leitin, F. Misselvits, E. V. Lyubimova, and V. S. Repin,Probl. Gematol.,27, 56–60 (1982).Google Scholar
  2. 2.
    H. R. Baumgartner,Thromb. Haemost,37, 1–16 (1977).PubMedGoogle Scholar
  3. 3.
    J. P. Cazenave, D. Blondowska, M. Richardson,et al., J. Clin. Lab. Med.,93, 60–66 (1979).Google Scholar
  4. 4.
    M. B. Stemerman,Progr. Haemost. Thromb.,2, 1–47 (1974).Google Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • I. P. Stepanova
    • 1
  • S. P. Domogatskii
    • 1
  1. 1.Group of Engineering Immunology, Cardiological Research CenterRussian Academy of Medical SciencesMoscow

Personalised recommendations