Bulletin of Experimental Biology and Medicine

, Volume 117, Issue 1, pp 78–83 | Cite as

Effect of extract from a transplant for eyelid plasty (series ALLOPLANTTM) on DNA synthesis in cultures cells

  • E. R. Muldashev
  • T. J. Wimen
  • N. N. Kurchatova
  • N. P. Zimina
  • A. S. Gur'yanov
  • K. S. Inchenko
Oncology

Abstract

Extract isolated from a collagen-containing transplant (series ALLOPLANTTM), which is used in the treatment of benign and malignant neoplasms of the eyelid, inhibits DNA synthesis in the cellin vitro. This effect is nonspecific, reversible, and dose-dependent. The extract is thermostable and resistant to proteolytic enzymes.

Key Words

eyelid plasty transplant extract DNA synthesis cell culture ALLOPLANTTM 

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References

  1. 1.
    M. J. Bissel and M. H. Barcellos-Hoss,J. Cell Sci., Suppl. 8, 327–343 (1987).Google Scholar
  2. 2.
    M. J. Bissel and T. J. Ram,Regulation of Functional Cytodifferentiation and Histogenesis in Mammary Epithelial Cells. Role of the Extracellular Matrix.Environmental Health Perspectives, Vol. 80, (1989), pp. 61–70.Google Scholar
  3. 3.
    R. R. Bruns and J. Gross,Exp. Cell Res.,128, 1–7 (1980).PubMedCrossRefGoogle Scholar
  4. 4.
    B. Carloz, B. Coulomb, C. Lebreton, and L. Duberted,Biomat. Artif. Cells Artif. Organs,16, 851 (1988).Google Scholar
  5. 5.
    J. J. Castellot, J. Choay, J. C. Lormeau,et al., Dermal Equivalent Culture Model and Interferon.J. Biol. Chem., Vol. 102, 1979–1984 (1986).Google Scholar
  6. 6.
    L. S. Culter,Adv. Dent. Res.,4, 27–33 (1990).Google Scholar
  7. 7.
    C. J. Doillon, F. H. Silver, and R. A. Berg,Biomaterials,9, 195–199 (1987).CrossRefGoogle Scholar
  8. 8.
    C. J. Doillon, A. J. Wasserman, R. A. Berg, and F. H. Silver,,8, 91–96 (1988).CrossRefGoogle Scholar
  9. 9.
    R. I. Freshney,Culture of Animal Cells. A Manual of Basic Technique, Alan R. Liss, Inc, New York (1987), pp. 236–237.Google Scholar
  10. 10.
    C. Guidry and F. Grinnell,Collagen Rel. Res., No 6, 515–529 (1986).Google Scholar
  11. 11.
    M. A. Hadley, S. W. Byers, C. A. Suares-Quian,et al., J. Cell Biol.,101, 1511–1522 (1986).CrossRefGoogle Scholar
  12. 12.
    A. A. Hakim,Collagen and Relat. Res., No 8, 519–520 (1988).Google Scholar
  13. 13.
    J. F. Hansdrough, S. T. Boyce, M. L. Cooper, and T. J. Foreman,JAMA,262, 2125–2130 (1989).CrossRefGoogle Scholar
  14. 14.
    E. D. Hay (Ed.),Cell Biology of the Extracellular Matrix, Plenum Press, New York (1981).Google Scholar
  15. 15.
    R. M. Hoffmann, K. M. Connors, A. Z. Meerson-Monosov,et al., Proc. Nat. Acad. Sci. USA,86, 2013–2017 (1989).CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • E. R. Muldashev
    • 1
    • 2
  • T. J. Wimen
    • 1
    • 2
  • N. N. Kurchatova
    • 1
    • 2
  • N. P. Zimina
    • 1
    • 2
  • A. S. Gur'yanov
    • 1
    • 2
  • K. S. Inchenko
    • 1
    • 2
  1. 1.Russian Center for Eye and Plastic SurgeryUfaRussia
  2. 2.James Weham Brown Oncology CenterLouisville UniversityUSA

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