Bulletin of Experimental Biology and Medicine

, Volume 117, Issue 1, pp 8–11 | Cite as

The invertor mechanism of changes in the plasma membranes of hepatocytes during induction of microsomal monooxygenases in adult and old rats

  • V. V. Frol'kis
  • A. L. Kobzar'
  • G. I. Paramonova


Age-specific changes of some parameters of the state of the plasma membrane are studied for genetic induction of enzymes of microsomal oxidation. Changes of the state of plasma membrane of hepatocytes are shown to be associated with the synthesis of a specific intracellular regulator (invertor).

Key Words

plasma membranes microsomal oxidation phenobarbital aging 


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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • V. V. Frol'kis
    • 1
  • A. L. Kobzar'
    • 1
  • G. I. Paramonova
    • 1
  1. 1.Laboratory of Physiology, Institute of GerontologyUkrainian Academy of Medical SciencesKiev

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