Skip to main content
Log in

Pulsatile blood flow in a stenosed artery—a theoretical model

  • Published:
Medical and Biological Engineering and Computing Aims and scope Submit manuscript

Abstract

To understand the special flow conditions which may be produced by the presence of stenosis in arteries, an analytical solution is obtained for pulsatile laminar flow in an elliptic tube. Blood is approximated by a Newtonian model and the geometry of the stenosis is introduced by specifying the change in area of cross-section of the stenosed artery with axial distance. The results for velocity, pressure, shear stress and impedance are presented. These are compared with the steady flow results as well as with those of the flow in a stenosed tube of circular cross-section. The study indicates that the fluid dynamic characteristics of the flow are affected by the percentage of stenosis as well as the geometry of the stenosis. The frequency of oscillation is also found to influence shearing stress and the impedance.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Attinger, E. O. (1963) Transmission in pulmonary arteries.Circ. Res.,12, 623–641.

    Google Scholar 

  • Caro, C. G. andSaffman, P. G. (1965) Extensibility of blood vessels in isolated rabbit lungs.J. Physiol.,178, 193–210.

    Google Scholar 

  • Caro, C. G., Fitz-Gerald, J. M. andSchroter, R. C. (1971) Atheroma and arterial wall shear-observation, correlation and proposal of a shear dependent mass transfer mechanism for Atherogensis.Proc. R. Soc. London,B177, 109–159.

    Article  Google Scholar 

  • Caro, C. G., Pedley, T. J., Schroter, R. C. andSeed, W. A. (1978)The mechanics of the circulation. Oxford University Press, New York, 346.

    Google Scholar 

  • Clark, C. (1976) The fluid mechanics of aortic stenosis: II unsteady flow experiments.J. Biomech.,9, 567–578.

    Article  Google Scholar 

  • Daly, B. J. (1976) A numerical study of pulsatile flow through stenosed canine femoral arteries.,9, 465–475.

    Article  Google Scholar 

  • Deshpande, M. D., Giddens, D. P. andMabon, R. F. (1976) Steady laminar flow through modelled vascular stenoses.,9, 165–174.

    Article  Google Scholar 

  • Fry, D. L. (1969) Certain histological and clinical responses for the vascular interface to acutely induced mechanical stress in the artery of the dog.Circ. Res.,24, 93–108.

    Google Scholar 

  • Lee, J. S. andFung, Y. C. (1970) Flow in a locally constricted tube at low Reynolds numbers.J. Appl. Mechs., Trans. ASME,37, 9–16.

    MATH  Google Scholar 

  • Padmanabhan, N. (1980) Mathematical model of arterial stenosis.Med. & Biol. Eng. & Comput.,18, 261–266.

    Article  Google Scholar 

  • Pedley, T. J. (1980)The fluid mechanics of large blood vessels. Cambridge University Press, Cambridge.

    MATH  Google Scholar 

  • Young, D. F. (1968) Etfect of a time dependent stenosis on flow through a tube.J. Eng. for Ind., Trans. ASME,90, 248–254.

    Google Scholar 

  • Young, D. F. andTsai, F. Y. (1973) Flow characteristics in models of arterial stenosis: I steady flow.J. Biomech.,6, 394–410.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mehrotra, R., Jayaraman, G. & Padmanabhan, N. Pulsatile blood flow in a stenosed artery—a theoretical model. Med. Biol. Eng. Comput. 23, 55–62 (1985). https://doi.org/10.1007/BF02444028

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02444028

Keywords

Navigation