Physicochemical properties of membranes and functional status of liver mitochondria in rats with an inherited capacity for increased radical formation
- 18 Downloads
Liver mitochondria of inbred W/SSM rats with inherited increased radical formation reveal the following anomalies: inhibition of oxidative phosphorylation, a lowered transmembrane potential, and alterations in protein-lipid interaction. The membrane viscosity and osmotic stability of mitochondria are unaffected.
Key Wordsrats of the W/SSM strain oxygen radicals mitochondria oxidative phosphorylation membrane structure
Unable to display preview. Download preview PDF.
- 1.G. E. Dobretsov,Fluorescent Probes in the Study of Cells, Membranes, and Lipoproteins [in Russina], Moscow (1989).Google Scholar
- 2.N. A. Solov'eva, T. S. Morozkova, and R. I. Salganik,Genetika, No. 5, 63–71 (1975).Google Scholar
- 3.N. A. Solov'eva, E. Kh. Ginzburg, F. S. Kazarinova,et al., Vopr. Med. Khim., No. 6, 41–47 (1987).Google Scholar
- 6.J. A. Imlay and S. Linn,Science,340, 1302–1309 (1988).Google Scholar