Bulletin of Experimental Biology and Medicine

, Volume 119, Issue 6, pp 567–570 | Cite as

Adaptation to altitude hypoxia limits lipid peroxidation during inflammation and stress

  • V. V. Malyshev
  • L. S. Vasil'eva
  • S. B. Belogorov
  • T. V. Nefedova
Pathological Physiology and General Pathology
  • 20 Downloads

Abstract

Preadaptation of rats to altitude hypoxia results in reduced activation of lipid peroxidation during subsequent stress, inflammation, or both, as compared to hypoxiaunadapted animals, with the result that secondary changes in organs and tissues of adapted rats are much less pronounced and conditions are created for alleviating the acute inflammation and the stress reaction.

Key Words

adaptation to hypoxia lipid peroxidation inflammation stress 

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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • V. V. Malyshev
    • 1
  • L. S. Vasil'eva
    • 1
  • S. B. Belogorov
    • 1
  • T. V. Nefedova
    • 1
  1. 1.Central Research LaboratoryMedical InstituteIrkutsk

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