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Transventricular defibrillation thresholds using quarter and half sinusoidal pulses

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Abstract

Transventricular peak current defibrillation thresholds using quarter (5 ms) and half (10 ms) sinusoidal pulses were determined in dogs under conditions of normothermia. For 5 ms, the overall average was 59·6 mAg−1 of heart (s.d. 21·00) in a total of ten animals and 88 successful defibrillations. For 10 ms, the average over seven dogs and 51 determinations was 52·5 mAg−1 of heart (s.d. 15·4). This difference was not statistically significant, whereas the energy delivered in the latter was about twice as much as in the former, suggesting the quarter sine wave pulse was better for defibrillation. A tighter definition of threshold is also introduced, i.e. the midrange between the maximum value which did not defibrillate and the minimum that did defibrillate. Such a definition is more realistic because it takes into account the successful and also the unsuccessfulvalues within a band of overlapping data points. The thresholds so obtained (52·3 mAg−1, s.d. 15·7, nine dogs, 5 ms; 42·9 mAg−1, s.d. 6·56, fourdogs, 10 ms) were, as expected, somewhat lower than the above mentioned ones showing, at the same time, lower coefficients of variation.

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Authors and Affiliations

  1. Departmento Bioingenieria, Instituto Superior de Investigaciones Biológicas, CONICET, Universidad Nacional de Tucumán, San Miguel de Tucumán, Árgentina

    J. E. Monzón

  2. Laboratorio Bioingenieria, Instituto Ingeniería Eléctrica, FACET, Universidad Nacional de Tucumán, San Miguel de Tucumán, Argentina

    M. E. Valentinuzzi

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  1. J. E. Monzón
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  2. M. E. Valentinuzzi
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Monzón, J.E., Valentinuzzi, M.E. Transventricular defibrillation thresholds using quarter and half sinusoidal pulses. Med. Biol. Eng. Comput. 20, 756–760 (1982). https://doi.org/10.1007/BF02442532

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  • DOI: https://doi.org/10.1007/BF02442532

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