Generation of a submicrometre nicotine aerosol for inhalation

  • J. E. Lux
  • R. C. Frecker
Technical Note


Aerosol Inhalation Nicotine 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Armitage, A. K. andTurner, D. M. (1970) Absorption of nicotine in cigarette and cigar smoke through the oral mucosa.Nature,226, 1231–1232.CrossRefGoogle Scholar
  2. Armitage, A. K., Dollery, C. T., George, C. F., Houseman, T. H., Lewis, P. J. andTurner, D. M. (1975) Absorption and metabolism of nicotine from cigarettes.Br. Med. J.,4, 313–316.Google Scholar
  3. Benowitz, N. L., Jacob, P., Jones, R. T. andRosenberg, J. (1982) Interindividual variability in the metabolism and cardiovascular effects of nicotine in man.J. Pharmacol. Exp. Ther.,221, 368–372.Google Scholar
  4. Dolovich, M., Ryan, G. andNewhouse, M. T. (1981) Aerosol penetration into the lung.Chest800, 834.Google Scholar
  5. Herning, R. I., Jones, R. T., Benowitz, N. L. andMines, A. H. (1983) How a cigarette is smoked determines nicotine blood levels.Clin. Pharmacol. Ther.,33, 84–90.CrossRefGoogle Scholar
  6. Heyder, J. (1982) Alveolar deposition of inhaled particles in humans.Am. Ind. Hyg. Assoc. J.,43, 864–866.Google Scholar
  7. Hinds, W. C. (1978) Size characteristics of cigarette smoke.,39, 48–54.Google Scholar
  8. Isaac, P. F. andRand, M. J. (1972) Cigarette smoking and plasma levels of nicotine.Nature,236, 308–310.CrossRefGoogle Scholar
  9. Jacob, P., Wilson, M. andBenowitz, N. L. (1981) Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids.J. Chromatography,222, 61–70.Google Scholar
  10. Karasek, F. W. (1978) Cascade particle analyzer.Ind. Res. Dev., Oct, 154–159.Google Scholar
  11. Russell, M. A. H., Feyerabend, C. andCole, P. V. (1976) Plasma nicotine levels after cigarette smoking and chewing nicotine gum.Br. Med. J.,1, 1043–1046.Google Scholar
  12. Russell, M. A. H., Jarvis, M. J., Feyerabend, C. andFerno, O. (1983) Nasal nicotine solution: a potential aid to giving up smoking?286, 683–684.CrossRefGoogle Scholar

Copyright information

© IFMBE 1988

Authors and Affiliations

  • J. E. Lux
    • 1
  • R. C. Frecker
    • 1
  1. 1.Institute of Biomedical Engineering and Department of PharmacologyUniversity of Toronto; Alcoholism & Drug Addiction Research FoundationTorontoCanada

Personalised recommendations