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The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction

European Journal of Clinical Pharmacology volume 44, pages 587–588 (1993)Cite this article

Summary

We have compared single oral doses of drinkable diclofenac dispersible (50 mg) with ibuprofen (400 mg) and placebo in a randomized, double-blind, parallel-group trial in 127 adults complaining of at least moderately severe pain after removal of an impacted third molar.

Within 40 min both diclofenac and ibuprofen produced significant pain relief that persisted for 6 h. There were no differences between diclofenac and ibuprofen in analgesic efficacy.

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Author information

Affiliations

  1. Department of Oral Surgery, Institute of Postgraduate Dental Education, P.O. Box 1030, S-55111, Jönköping, Sweden

    U. Ahlström & P. Nilsson

  2. Medical Department, Ciba-Geigy AG, Basel, Switzerland

    R. Bakshi

  3. Medical Department, Ciba-Geigy AB, Västra Frölunda, Sweden

    L. Wåhlander

Authors
  1. U. Ahlström
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  2. R. Bakshi
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  3. P. Nilsson
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  4. L. Wåhlander
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Ahlström, U., Bakshi, R., Nilsson, P. et al. The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction. Eur J Clin Pharmacol 44, 587–588 (1993). https://doi.org/10.1007/BF02440865

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  • DOI: https://doi.org/10.1007/BF02440865

Key words

  • Analgesia
  • Diclofenac
  • Ibuprofen
  • post-operative pain
  • dental surgery