Skip to main content

Clinical and morphological aspects of laryngeal cysts

Abstract

To our knowledge only a few defined studies have been carried out on laryngeal cysts. These cysts represent a mixed group of benign laryngeal lesions that can cause diagnostic and therapeutic difficulties. The aim of this study was to characterize their histological structure and localizations in the larynx as well as to discuss theories about their genesis. Between 1973 and 1996, 342 laryngeal cysts were treated at Phillips University of Marburg, while from 1990 to 1996, 74 were treated at Justus Liebig University of Giessen. In all, 416 laryngeal cysts were treated by endolaryngeal microsurgery. All clinical charts were reviewed retrospectively and surgical specimens examined histomorphologically. Findings showed that 58.2% of the laryngeal cysts were located in the glottic area and 18.3% in the ventricular folds. The remainder were located on the aryepiglottic fold (2.2%) and interarythenoid region (0.7%). Two congenital cysts were also treated. Approximately 56% of the laryngeal cysts were lined by squamous cell epithelium, 37% by respiratory epithelium and 7% by oncocytic epithelium. In general, the laryngeal cysts were found to be a collection of inhomogenous lesions from different histogenetic origins with diverse symptoms related to their site and size. On the basis of our investigations, a new classification was established concerning the genesis and development of laryngeal cysts by subdividing cysts into congenital cysts, retention cysts, and inclusion cysts.

This is a preview of subscription content, access via your institution.

References

  1. Abramson AL, Zielinski B (1984) Congenital laryngeal saccular cyst of the newborn. Laryngoscope 94:1580–1582

    PubMed  CAS  Google Scholar 

  2. Albanese S, Kleinsasser O (1988) Kongenitale Zysten des Larynx. Laryngol Rhinol Otol 67:282–285

    CAS  Article  Google Scholar 

  3. Bouchayer M, Cornut G (1974) Cystes et pseudocystes de la corde vocale. C R Seances Cong Fr ORL. Arnette, Paris

    Google Scholar 

  4. Bouchayer M, Cornut G (1992) Microsurgical treatment of benign vocal fold lesions: indications, technique, results. Folia Phoniatr Logop 44:155–184

    CAS  Article  Google Scholar 

  5. Bouchayer M, Cornut G, Witzig E, Bastian RW (1985) Epidermoid cysts, sulci and mucosal bridges of the true vocal cord: a report of 157 cases. Laryngoscope 95: 1087–1094

    PubMed  CAS  Google Scholar 

  6. De Santo LW, Devibe KD, Weiland LH (1970) Cysts of the larynx. Classification. Laryngoscope 80:145–176

    Google Scholar 

  7. Eckert-Möbius A (1966) Lehrbuch der Hals-Nasen-Ohrenheilkunde. VEB Thieme, Leipzig

    Google Scholar 

  8. Grossenbacher R (1995) CO2 laser surgery for benign lesions of the vocal cords. Otorhinolaryngol 49: 158–161

    CAS  Google Scholar 

  9. Grundmann EW (1979) Retentionszysten der Stimmlippen. HNO 27:156–158

    PubMed  CAS  Google Scholar 

  10. Holinger LD, Barnes DR, Smid LJ (1978) Larnygocele and saccular cysts. Ann Otol Rhinol Laryngol 87:675–685

    PubMed  CAS  Google Scholar 

  11. Holinger PH, Johnston KC (1951) Benign tumors of the larynx. Ann Otol 60:496–509

    CAS  Google Scholar 

  12. Kleinsasser O (1991) Mikrolaryngoskopie and endolaryngeale Mikrochirurgie, 3rd edn. Schattauer, Stuttgart

    Google Scholar 

  13. Louys E (1899) Des kystes intralaryngées et en part des kystes laryngées branchiogenes. Rev Chir Paris 19:653

    Google Scholar 

  14. Matzker J (1963) Gutartige Tumoren des Kehlkopfes. In: Berendes J, Link R, Zöllner F (eds) Handbuch der Hals-Nasen-Ohrenheilkunde. Thieme, Stuttgart

    Google Scholar 

  15. Meyer-Breiting E, Burkhardt A (1988) Pseudotumors of the larynx. In: Tumors of the larynx. Histopathology and clinical inferences. Springer, Berlin Heidelberg New York

    Google Scholar 

  16. Michaels L (1984) Pathology of the larynx. Springer, Berlin Heidelberg New York

    Google Scholar 

  17. Mitchell DB, Irwin BC, Bailey BS, Evans NG (1987) Cysts of infant larynx. J Laryngol Otol 101: 833–837

    PubMed  CAS  Google Scholar 

  18. Monday LA, Corunt G, Bouchayer M, Roch JB (1983) Epidermoid cysts of the vocal cords. Ann Otol 92: 124–127

    CAS  Google Scholar 

  19. Myerson MC (1933) Cysts of the larynx. Arch Otolaryngol 18: 281–290

    Google Scholar 

  20. Newman BH, Taxy JB, Laker HI (1984) Laryngeal cysts in adults: a clinicopathologic study of 20 cases. Am J Clin Pathol 81:715–720

    PubMed  CAS  Google Scholar 

  21. Oliveira CA, Roth JA, Adams GL (1977) Oncocytic lesions of the larynx. Laryngoscope 87:1718–1724

    PubMed  CAS  Google Scholar 

  22. Ramesar K, Albizzati C (1988) Laryngeal cysts: clinical relevance and modified working classification. J Laryng Otol 102: 923–925

    CAS  Google Scholar 

  23. Ruckes J, Matzker J (1960) Der dyschylische Tumor der Taschenlippe. Z Laryngol Rhinol Otol 39:796–806

    PubMed  CAS  Google Scholar 

  24. Smith JD, Cotton R, Meyer CM III (1990) Subglottic cysts in the premature infant. Arch Otolaryngol Head Neck Surg 116: 479–482

    PubMed  CAS  Google Scholar 

  25. Toriumi DM, Miller DR, Holinger LD (1987) Acquired subglottic cysts in premature infants. Int J Pediatr Otorhinolaryngol 14:151–160

    PubMed  CAS  Article  Google Scholar 

  26. Triglia JM, Portaspana T, Cannoni M, Pech A (1991) Subglottic cysts in a newborn. J Laryngol Otol 105:222–223

    PubMed  CAS  Google Scholar 

  27. Werkhaven J, Ossoff RH (1991) Laryngeal cysts. Surgery for benign lesions of the glottis. Voice disorders. Otolaryngol Clin North Am 24:1195–1197

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Arens, C., Glanz, H. & Kleinsasser, O. Clinical and morphological aspects of laryngeal cysts. Eur Arch Otorhinolaryngol 254, 430 (1997). https://doi.org/10.1007/BF02439974

Download citation

  • Received:

  • Accepted:

  • DOI: https://doi.org/10.1007/BF02439974

Key words

  • Larynx
  • Cysts
  • Classification
  • Therapy