Abstract
Earlier studies in young growing rabbits have suggested that post-traumatic developmental deformities of the cricoid might play a role in failing treatment in children with similar injuries. Specific patterns of malformations in the animals occurred preferentially at the anterior side of the cricoid ring. In this study, the growth dynamics of the cricoid were studied by histometry and autoradiography. Results indicated that (1) the cell/matrix ratio remains unchanged from 4 to 24 weeks of age, with both tissue components thus contributing equally to growth of the cricoid; (2) mitoses occur in cartilage and perichondrium, indicating interstitial as well as appositional growth; (3) mitotic activity is mainly restricted to the first 4 weeks of life, while cell hypertrophy is thereafter the dominant feature; (4) the highest degree of mitotic activity and cell hypertrophy is found in the anterior half of the cricoid ring which therefore can be considered as a growth center. This center might play a role in the development of trauma-induced deformation in the anterior part of the cricoid ring.
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Adriaansen FCPM, Verwoerd-Verhoef HL, Heul R vd, Verwoerd CDA (1986) A morphometric study of the growth of the subglottis after endolaryngeal trauma. Int J Pediatr Otorhinolaryngol 12: 217–226
Adriaansen FCPM, Verwoerd-Verhoef HL, Heul R vd, Verwoerd CDA (1986) A histologic study of the growth of the subglottis after endolaryngeal trauma. Int J Pediatr Otorhinolaryngol 12:205–215
Adriaansen FCPM, Verwoerd-Verhoef HL, Heul R vd, Verwoerd CDA (1988) Differential effects of endolaryngeal trauma upon the growth of the subglottis. Int J Pediatr Otorhinolaryngol 15:163–171
Bean JK, Verwoerd-Verhoef HL, Adriaansen FCPM, Verwoerd CDA (1992) The influence of ageing on wound healing of the cricoid. Acta Otolaryngol (Stockh) 112: 362–365
Bean JK, Verwoerd-Verhoef HL, Verwoerd CDA (1995) Injury- and age-linked differences in wound healing and stenosis formation of the subglottis. Acta Otolaryngol (Stockh) 115: 317–321
Copray JCVM (1986) Growth of the nasal septal cartilage of the rat in vitro. J Anat 144: 99–111
Copray JCVM, Jansen HWB, Duterloo HS (1983) Growth of the mandibular condylar cartilage of the rat in serum-free organ culture. Arch Oral Biol 28: 967–974
Cotton RT, Evans JNG (1981) Laryngotracheal reconstruction in children: five year follow-up. Ann Otol Rhinol Laryngol 90: 516–520
Crysdale WS, Crepeau J (1982) Surgical correction of subglottic stenosis in children. J Otolaryngol 11: 209–213
Holinger LD, Stankiewicz J, Livingston GL (1987) Anterior cricoid split: the Chicago experience with an alternative to tracheotomy. Laryngoscope 97: 19–24
Jackson C, Jackson CL (1932) Laryngeal stenosis — growth of the larynx as a factor in treatment. Laryngoscope 2: 887–889
Kahane JC (1982) Growth of the human prepubertal and pubertal larynx. J Speech Hear Res 25: 446–455
Morimoto K, Kobayashi K, Shimoda K, Kataura A (1985) Surgical correction of subglottic stenosis in children; a follow-up study. ORL 47: 178–185
Stell PM, Stanley RE, Maran AGD, Murray JAM (1985) Chronic laryngeal stenosis. Ann Otol Rhinol Laryngol 94: 108–113
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Verwoerd-Verhoef, H.L., Adriaansen, F.C.P.M., Laeijendecker, R.J. et al. Growth dynamics of the cricoid cartilage and subglottic injury. Eur Arch Otorhinolaryngol 254 (Suppl 1), S101–S104 (1997). https://doi.org/10.1007/BF02439736
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DOI: https://doi.org/10.1007/BF02439736