Quantitative and predictive correlations for peroxidase catalysis in organic media

  • Keungarp Ryu
  • Jonathan S. Dordick
Article

Summary

Quantitative and predictive relationships have been developed for horseradish peroxidase catalysis in both aqueous and organic media. These relationships take into account the physicochemical characteristics of both substrate (e.g., hydrophobicity and electronic characteristics) and solvent (e.g., hydrophobicity and polarity). The results suggest that solvent effects on hydrophobic interactions within proteins are secondary to effects on electrostatic forces.

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Copyright information

© Science & Technology Letters 1992

Authors and Affiliations

  • Keungarp Ryu
    • 1
  • Jonathan S. Dordick
    • 1
  1. 1.Department of Chemical and Biochemical EngineeringUniversity of IowaIowa City

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