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Effect of pineal tetrapeptide on antioxidant defense inDrosophila melanogaster

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Effect of synthetic pineal tetrapeptide L-Ala-L-Glu-L-Asp-L-Glu (Epithalon) on specific catalase activity and the content of conjugated hydroperoxides in highly inbredDrosophila melanogaster lines differing in reproductive functions were studied. It was shown that Epithalon is a potent modulator of the antioxidant defense, whose biological activity 1000-fold surpasses that of the complex pineal peptide preparation Epithalamin.

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Khavinson, V.K., Myl'nikov, S.V. Effect of pineal tetrapeptide on antioxidant defense inDrosophila melanogaster . Bull Exp Biol Med 129, 355–356 (2000). https://doi.org/10.1007/BF02439268

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  • DOI: https://doi.org/10.1007/BF02439268

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