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Elevated basal activity of tryptophan oxygenase in alcohol-preferring C57Bl mice

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Tryptophan oxygenase activity in alcohol-preferring C57Bl mice and control CBA and DBA/2 mice was studied under nonstressful conditions and after glucocorticoid-induced stress. Elevated basal tryptophan oxygenase activity in C57Bl mice is probably responsible for reduced brain content of tryptophan and serotonin associated with alcohol preference.

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Authors and Affiliations

  1. Institute of Cytology, and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk

    E. D. Vasil'eva, T. V. Yakovleva, S. I. Il'nitskaya & G. V. Vasil'ev

Authors
  1. E. D. Vasil'eva
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  2. T. V. Yakovleva
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  3. S. I. Il'nitskaya
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  4. G. V. Vasil'ev
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 4, pp. 408–410, April, 2000

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Vasil'eva, E.D., Yakovleva, T.V., Il'nitskaya, S.I. et al. Elevated basal activity of tryptophan oxygenase in alcohol-preferring C57Bl mice. Bull Exp Biol Med 129, 346–347 (2000). https://doi.org/10.1007/BF02439264

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  • DOI: https://doi.org/10.1007/BF02439264

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